Atopica 100 mg (15 gel Caps) Atopica 100 mg (15 gel Caps) 
Description and Composition Soft gel
capsule of 4 strenghts are available: ATOPICA contains 10 mg,
25 mg, 50 mg or 100 mg Cyclosporine A per
capsule. List of excipients: Tocopherol (E-307), iron oxide black
(E 172), titanium dioxide (E 171), edible red ink, excip.
ad sol.. Properties ATOPICA contains Cyclosporine A (ATCvet code
QL04A A) a selective immunomodulator. It is a cyclic polypeptide
consisting of 11 amino acids with a molecular weight of
1203 Daltons which acts specifically and reversibly on T-lymphocytes. Cyclosporine
has anti-inflammatory and anti-pruritic activities in atopic dermatitis. Cyclosporine acts
specifically and reversibly on resting T-lymphocytes and inhibits the antigen-triggered
release of lymphokines by activated T-cells. It also inhibits eosinophil
recruitment and activation, keratinocyte cytokine production, Langerhans' cell functions, degranulation
of mastocytes and therefore release of histamine and pro inflammatory
cytokines. Cyclosporine does not depress hemopoiesis and has no effect
on the function of phagocytic cells. A prescription
isrequired for this product. Click here for details
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